Histace, A, Bonnefoye, E, Garrido, L, Matuszewski, Bogdan and Murphy, M (2014) Active contour segmentation based on approximate entropy: Application to cell membrane segmentation in confocal microscopy. In: 7th International Conference on Bio-Inspired Systems and Signal Processing, BIOSIGNALS 2014 - Part of 7th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014, 3rd March 2014 - 6th March 2014, Angers, Loire Valley.
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Segmentation of cellular structures is of primary interest in cell imaging for cell shape reconstruction and to provide crucial information about possible cell morphology changes during radiotherapy for instance. From the particular perspective of predictive oncology, this paper reports on a novel method for membrane segmentation from single channel actin tagged fluorescence confocal microscopy images, which remains a challenging task. Proposed method is based on the use of the Approximate Entropy formerly introduced by Pincus embedded within a Geodesic Active Contour approach. Approximate Entropy can be seen as an estimator of the regularity of a particular sequence of values and, consequently, can be used as an edge detector. In this prospective study, a preliminary study on Approximate Entropy as an edge detector function is first proposed with a particular focus on the robustness to noise, and some promising membrane segmentation results obtained on confocal microscopy images are also shown. Copyright © 2014 SCITEPRESS - Science and Technology Publications. All rights reserved.
|Item Type:||Conference or Workshop Item (Paper)|
|Additional Information:||BIOSIGNALS 2014 - 7th Int. Conference on Bio-Inspired Systems and Signal Processing, Proceedings; Part of 7th Int. Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014,SciTePress, 9789897580116 (ISBN)|
|Uncontrolled Keywords (separate with ;):||Active Contours; Approximate Entropy; Confocal Microscopy; Image Segmentation; Biomedical engineering; Cell membranes; Confocal microscopy; Cytology; Entropy; Proteins; Signal processing Active contour segmentation; Active contours; Approximate entropy; Cellular structure; Fluorescence confocal microscopy; Geodesic Active Contour; Membrane segmentation; Robustness to noise; Image segmentation|
|Subjects:||Engineering > Civil engineering|
|Schools:||Faculty of Science and Technology > School of Engineering|
|Deposited By:||Helen Cooper|
|Deposited On:||25 Jul 2014 08:22|
|Last Modified:||17 May 2016 12:49|
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