Duff, Alistair J.A., Abbott, Janice, Cowperthwaite, Carolyn, Sumner, Clare, Hurley, Margaret Anne and Quittner, Alexandra (2014) Depression and anxiety in adolescents and adults with cystic fibrosis in the UK: A cross-sectional study. Journal of Cystic Fibrosis, 13 (6). pp. 745-753. ISSN 15691993
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Official URL: http://dx.doi.org/10.1016/j.jcf.2014.02.010
The International Depression/anxiety Epidemiological Study (TIDES) in the UK aimed: (i) to establish the prevalence of anxiety and depression amongst people with CF compared to a normative sample; (ii) to establish the association between mood, demographic and clinical variables; and (iii) to provide guidance for specialist-referral decision-making.
Patients (≥ 12 years) completed the Hospital Anxiety and Depression Scale (HADS). CF-HADS scores, expressed as percentiles, were compared with a normative sample. Multiple-regression analysis explored associations between demographic, clinical and mood variables.
Thirty-nine CF centres recruited 2065 patients. Adults with CF were similar in terms of anxiety and depression to the general population. Adolescents with CF were less anxious and depressed. For adult patients, older age, unemployment for health reasons and poor lung function were associated with disordered mood. Gender-specific CF-percentile scores were calculated.
Surveillance, with attention to gender and risk factors is advocated. This work provides unique benchmark scores to aid referral decision-making.
|Subjects:||C - Biological sciences > C800 - Psychology|
|Schools:||Faculty of Science and Technology > School of Psychology|
Faculty of Health and Wellbeing > Research Support Team
|Deposited By:||Janice Abbott|
|Deposited On:||19 Jan 2015 10:49|
|Last Modified:||19 Oct 2016 17:10|
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