Ameen, Dana and Snape, Timothy James (2014) Developing the Scope of O→C Aryl Migrations: Exploring Amide Substrates as Potential Precursors for Asymmetric Reactions. European Journal of Organic Chemistry, 2014 (9). pp. 1925-1934. ISSN 1434-193X
PDF (Version of Record)
- Published Version
Restricted to Repository staff only
Available under License Creative Commons Attribution Non-commercial No Derivatives.
Official URL: http://dx.doi.org/10.1002/ejoc.201301716
A new and mild method for the production of diasteromerically enriched α-aryl carbonyl compounds has been achieved. Although only modest diastereoselectivies are observed, they demonstrate the potential of the method for further optimisation. It also appears that reactions that proceed through a five-membered spirocyclic transition state rearrange, whereas those proceeding through a six-membered transition state do not, but stop at the diaryl ether stage.
|Subjects:||Physical sciences > Chemistry|
|Schools:||Faculty of Clinical & Biomedical Sciences > School of Pharmacy and Biomedical Sciences|
|Deposited By:||Timothy James Snape|
|Deposited On:||17 Apr 2015 12:07|
|Last Modified:||16 Mar 2017 12:59|
Downloads per month over past year
Downloads for past 30 days
Repository Staff Only: item control page