Timing of Allergenic Food Introduction to the Infant Diet and Risk of Allergic or Autoimmune Disease

Abstract

Importance Timing of introduction of allergenic foods to the infant diet may influence the risk of allergic or autoimmune disease, but the evidence for this has not been comprehensively synthesized.

Objective To systematically review and meta-analyze evidence that timing of allergenic food introduction during infancy influences risk of allergic or autoimmune disease.

Data Sources MEDLINE, EMBASE, Web of Science, CENTRAL, and LILACS databases were searched between January 1946