Aljabali, Alaa AA, Hassan, Sk Sarif, Pabari, Ritesh M, Shahcheraghi, Seyed H, Mishra, Vijay, Charbe, Nitin B, Chellappan, Dinesh K, Dureja, Harish, Gupta, Gaurav , Almutary, Abdulmajeed G, Alnuqaydan, Abdullah M, Verma, Suresh K, Panda, Pritam K, Mishra, Yogendra Kumar, Serrano-Aroca, Ángel, Dua, Kamal, Uversky, Vladimir N, Redwan, Elrashdy M, Bahar, Bojlul ORCID: 0000-0002-7389-3650, Bhatia, Amit, Negi, Poonam, Goyal, Rohit, McCarron, Paul, Bakshi, Hamid A and Tambuwala, Murtaza M (hide)
(2021)
The viral capsid as novel nanomaterials for drug delivery.
Future Science OA, 7
(9).
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PDF (Version of Record)
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Available under License Creative Commons Attribution. 9MB |
Official URL: https://doi.org/10.2144/fsoa-2021-0031
Abstract
The purpose of this review is to highlight recent scientific developments and provide an overview of virus self-assembly and viral particle dynamics. Viruses are organized supramolecular structures with distinct yet related features and functions. Plant viruses are extensively used in biotechnology, and virus-like particulate matter is generated by genetic modification. Both provide a material-based means for selective distribution and delivery of drug molecules. Through surface engineering of their capsids, virus-derived nanomaterials facilitate various potential applications for selective drug delivery. Viruses have significant implications in chemotherapy, gene transfer, vaccine production, immunotherapy and molecular imaging.
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