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Selective Serotonin Reuptake Inhibitors for Stroke Recovery

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Hua, Xing, Wu, Simiao, Legg, Lynn A., Rudberg, Ann-Sofie, Hackett, Maree ORCID: 0000-0003-1211-9087, Tilney, Russel, Lindgren, Linnea, Kutlubaev, Mansur A., Hsieh, Cheng-Fang et al (2022) Selective Serotonin Reuptake Inhibitors for Stroke Recovery. Stroke, 53 (9). e426-e428. ISSN 1524-4628

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Official URL: https://doi.org/10.1161/STROKEAHA.121.038149

Abstract

Stroke is a major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression and other mood disorders after stroke. Small studies suggested that SSRIs might also promote motor recovery by direct effects on the brain. In this Cochrane review, we aimed to determine the effects of SSRIs in improving outcomes in people <12 months after stroke and to determine whether treatment with SSRIs is associated with adverse effects.

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