This short paper presents a deformable surface registration scheme which is based on the statistical shape modelling technique. The method consists of two major processing stages, model building and model fitting. A statistical shape model is first built using a set of training data. Then the model is deformed and matched to the new data by a modified iterative closest point (ICP) registration process. The proposed method is tested on real 3-D facial data from BU-3DFE database. It is shown that proposed method can achieve a reasonable result on surface registration, and can be used for patient position monitoring in radiation therapy and potentially can be used for monitoring of the radiation therapy progress for head and neck patients by analysis of facial articulation.