Meziou, Leila, Histace, Aymeric, Precioso, Frederic, Matuszewski, Bogdan J and Carreiras, Franck (2012) Fractional Entropy Based Active Contour Segmentation of Cell Nuclei in Actin-Tagged Confocal Microscopy Images. In: Medical Image Understanding and Analysis, 9-11 July 2011, Swansea, UK.
- Published Version
Official URL: http://miua2012.swansea.ac.uk/index.php?n=Site.Pro...
In the framework of cell structure characterization for predictive oncology, we propose in this paper an unsupervised statistical region based active contour approach integrating an original fractional entropy measure for single channel actin tagged fluorescence confocal microscopy image segmentation. Following description of statistical based active contour segmentation and the mathematical definition of the proposed fractional entropy descriptor, we demonstrate comparative segmentation results between the proposed approach and standard Shannon’s entropy obtained for nuclei segmentation. We show that the unsupervised proposed statistical based approach integrating the fractional entropy measure leads to very satisfactory segmentation of the cell nuclei from which shape characterization can be subsequently used for the therapy progress assessment.
|Item Type:||Conference or Workshop Item (Paper)|
|Subjects:||Computer science > Software engineering|
Engineering > Civil engineering
|Schools:||Faculty of Science and Technology > School of Engineering|
|Deposited By:||Bogdan Matuszewski|
|Deposited On:||09 Apr 2013 09:59|
|Last Modified:||17 May 2016 12:39|
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