Items where Author is "Snape, Timothy James"

Chetter, Ben, Kyriakis, Efthimios, Barr, Daniel, Karra, Aikaterini G., Katsidou, Elisabeth, Koulas, Symeon M., Skamnaki, Vassiliki T., Snape, Timothy James ORCID: 0000-0003-2766-4491, Psarra, Anna-Maria G. et al (2020) Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors. Bioorganic Chemistry, 102 (104003). ISSN 0045-2068

Barr, Daniel, Szennyes, Eszter, Bokor, Éva, Al-Oanzi, Ziad H., Moffatt, Colin, Kun, Sándor, Docsa, Tibor, Sipos, Ádám, Davies, Matthew et al (2019) Identification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies. ACS Chemical Biology, 14 (7). pp. 1460-1470. ISSN 1554-8929

Sherer, Christopher ORCID: 0000-0002-6422-9870, Prabhu, Saurabh, Adams, David R, Hayes, Joseph ORCID: 0000-0002-7745-9616, Rowther, Farzana, Tolaymat, Ibrahim, Warr, Tracy and Snape, Timothy James ORCID: 0000-0003-2766-4491 (2018) Towards identifying potent new hits for glioblastoma. MedChemComm, 9 (11). pp. 1850-1861. ISSN 2040-2503

Sherer, Christopher ORCID: 0000-0002-6422-9870, Tolaymat, Ibrahim, Rowther, Farzana, Warr, Tracy and Snape, Timothy James ORCID: 0000-0003-2766-4491 (2017) Preliminary SAR on indole-3-carbinol and related fragments reveals a novel anticancer lead compound against resistant glioblastoma cells. Bioorganic & Medicinal Chemistry Letters, 27 (7). pp. 1561-1565. ISSN 0960-894X

Snape, Timothy James ORCID: 0000-0003-2766-4491, Dennison, Sarah Rachel ORCID: 0000-0003-4863-9607 and Patil--sen, Yogita ORCID: 0000-0002-4286-8874 (2016) Functional foldamers that target bacterial membranes: the effect of charge, amphiphilicity and conformation. Bioorganic & Medicinal Chemistry, 24 (18). pp. 4241-4245. ISSN 0968-0896

Harris, Frederick, Prabhu, Saurabh, Dennison, Sarah Rachel ORCID: 0000-0003-4863-9607, Snape, Timothy James ORCID: 0000-0003-2766-4491, Lea, Robert William, Mura, Manuela and Phoenix, David Andrew (2016) Anionic Host Defence Peptides from the Plant Kingdom: Their Anticancer Activity and Mechanisms of Action. Protein and Peptide Letters, 23 (8). pp. 676-687. ISSN 0929-8665

Hester, Theodore James, Dennison, Sarah Rachel ORCID: 0000-0003-4863-9607, Baker, Matthew ORCID: 0000-0003-2362-8581 and Snape, Timothy James ORCID: 0000-0003-2766-4491 (2015) Functionalising the azobenzene motif delivers a light-responsive membrane-interactive compound with the potential for photodynamic therapy applications. Organic Biomolecular Chemistry, 13 (29). pp. 8067-8070. ISSN 1477-0520

Prabhu, Saurabh, Dennison, Sarah Rachel ORCID: 0000-0003-4863-9607, Mura, Manuela ORCID: 0000-0002-3913-7595, Lea, Robert William, Snape, Timothy James ORCID: 0000-0003-2766-4491 and Harris, Frederick (2014) Cn-AMP2 from green coconut water is an anionic anticancer peptide. Journal of Peptide Science, 20 (12). pp. 909-915. ISSN 1075-2617

Snape, Timothy James ORCID: 0000-0003-2766-4491, Fahs, Sara, Rowther, Farjana, Dennison, Sarah Rachel ORCID: 0000-0003-4863-9607, Patil-Sen, Yogita and Warr, Tracy (2014) Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity. Bioorganic & Medicinal Chemistry Letters, 24 (15). pp. 3430-3433. ISSN 0960-894X

Ameen, Dana and Snape, Timothy James ORCID: 0000-0003-2766-4491 (2014) Developing the Scope of O→C Aryl Migrations: Exploring Amide Substrates as Potential Precursors for Asymmetric Reactions. European Journal of Organic Chemistry, 2014 (9). pp. 1925-1934. ISSN 1434-193X

Lal, Samridhi and Snape, Timothy James ORCID: 0000-0003-2766-4491 (2014) Aromatic amides and ureas as novel molecular probes for diagnosing disease. Medical Hypotheses, 83 (6). pp. 751-754. ISSN 03069877

Snape, Timothy James ORCID: 0000-0003-2766-4491 and Ameen, Dana (2014) Mechanism and Application of Baker–Venkataraman O→C Acyl Migration Reactions. Synthesis, 47 (02). pp. 141-158. ISSN 0039-7881

Prabhu, Saurabh, Harris, Frederick, Lea, Robert William and Snape, Timothy James ORCID: 0000-0003-2766-4491 (2014) Small-molecule clinical trial candidates for the treatment of glioma. Drug Discovery Today, 19 (9). pp. 1298-1308. ISSN 13596446

Harris, Frederick, Prabhu, Saurabh, Lea, Robert William and Snape, Timothy James ORCID: 0000-0003-2766-4491 (2011) Characterisation of an anionic antimicrobial peptide isolated from green coconut water. In: UK-Netherlands Joint Symposium on Antimicrobial peptides: Isolation, characterization, modification and applications, 2011, University of Durham.

Prabhu, Saurabh, Harris, Frederick, Lea, Robert William and Snape, Timothy James ORCID: 0000-0003-2766-4491 (2011) Towards establishing the effects and mechanism of action of a series of substituted indoles in an in vitro chemosensitivity system for glioma treatment. In: Britsh Neuro-Oncology Annual Meeting, 2011, University of Glagow.

Ellis, Andrew J, Reiss, Renate, Snape, Timothy James ORCID: 0000-0003-2766-4491 and Turner, Nicholas (2009) Monoamine oxidase (MAO-N) catalysed reactions: application towards the chemo-enzymatic deracemisation of the alkaloid (+)- crispine A. In: Practical methods for biocatalysis and biotransformations. Wiley, London, pp. 319-322. ISBN 0470519274

Deplanche, K, Snape, Timothy James ORCID: 0000-0003-2766-4491, Hazrati, S., Harrad, S. and Macaskie, L. E. (2009) Versatility of a new bioinorganic catalyst: Palladized cells of Desulfovibrio desulfuricans and application to dehalogenation of flame retardant materials. Environmental Technology, 30 (7). p. 681. ISSN 0959-3330