Items where Author is "Somsák, László"

Homolya, Levente, Mathomes, Rachel Thelma ORCID: 0000-0002-1079-8509, Varga, Luca, Docsa, Tibor, Juhasz, Laszlo, Hayes, Joseph ORCID: 0000-0002-7745-9616 and Somsák, László (2024) Synthesis, in silico and kinetics evaluation of N-(β-D-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(β-D-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as glycogen phosphorylase inhibitors. International Journal of Molecular Sciences, 25 (9). ISSN 1661-6596

Kun, Sándor, Mathomes, Rachel Thelma ORCID: 0000-0002-1079-8509, Docsa, Tibor, Somsák, László and Hayes, Joseph ORCID: 0000-0002-7745-9616 (2023) Design and Synthesis of 3-(β-d-Glucopyranosyl)-4-amino/4-guanidino Pyrazole Derivatives and Analysis of Their Glycogen Phosphorylase Inhibitory Potential. Molecules, 28 (7). p. 3005.

Kiss, Mariann, Timári, István, Barna, Teréz, Mészáros, Zuzana, Slámová, Kristýna, Bojarová, Pavla, Křen, Vladimír, Hayes, Joseph ORCID: 0000-0002-7745-9616 and Somsák, László (2022) 2-Acetamido-2-deoxy- d -glucono-1,5-lactone Sulfonylhydrazones: Synthesis and Evaluation as Inhibitors of Human OGA and HexB Enzymes. International Journal of Molecular Sciences, 23 (3). e1037. ISSN 1661-6596

Kiss, Mariann, Szabó, Erna, Bocska, Boglárka, Sinh, Luu Thanh, Fernandes, Conceicao Piedade, Timári, István, Hayes, Joseph ORCID: 0000-0002-7745-9616, Somsák, László and Barna, Teréz (2021) Nanomolar inhibition of human OGA by 2-acetamido-2-deoxy-D-glucono-1,5-lactone semicarbazone derivatives. European Journal of Medicinal Chemistry, 223 . p. 113649. ISSN 0223-5234

Barr, Daniel, Szennyes, Eszter, Bokor, Éva, Al-Oanzi, Ziad H., Moffatt, Colin, Kun, Sándor, Docsa, Tibor, Sipos, Ádám, Davies, Matthew et al (2019) Identification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies. ACS Chemical Biology, 14 (7). pp. 1460-1470. ISSN 1554-8929

Kun, Sándor, Begum, Jaida, Kyriakis, Efthimios, Stamati, Evgenia C V, Barkas, Thomas A, Szennyes, Eszter, Bokor, Éva, Szabó, Katalin E, Stravodimos, George A et al (2018) A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors. European Journal of Medicinal Chemistry, 147 . pp. 266-278. ISSN 0223-5234

Begum, Jaida, Varga, Gergely, Docsa, Tibor, Gergely, Pál, Hayes, Joseph M. ORCID: 0000-0002-7745-9616, Juhász, László and Somsák, László (2015) Computationally motivated synthesis and enzyme kinetic evaluation of N-(β-d-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors. Med. Chem. Commun., 6 (1). pp. 80-89. ISSN 2040-2503