Items created by Alder, Jane Elizabeth

Article

Emmerich, Thomas D, Taylor-Chilton, Eleanor, Caballero, Elena, Hushcha, Iryna, Dickens, Kathryn ORCID: 0000-0003-0925-1538, Stasik, Izabela ORCID: 0000-0002-7756-4731, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Saavedra-Castano, Santiago, Berenschot, Erwin et al (2025) Structure-Based Discovery Targeting GSK-3α Reveals Potent Nanomolar Selective 4-Phenyl-1H-benzofuro[3,2-b]pyrazolo[4,3-e]pyridine Inhibitor with Promising Glioblastoma and CNS-Active Potential in Cellular Models. Journal of Medicinal Chemistry, 68 (8). pp. 8679-8693. ISSN 0022-2623

Taylor-Chilton, Eleanor, Baldwin, Lydia, Stead, Lucy, Greenman, John, Wade, Mark, Rabie, Tamer Bahaa eldin ORCID: 0000-0002-5551-7598 and Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 (2024) APPLICATION OF IN VITRO MODELS: INCORPORATING BLOOD BRAIN BARRIER MODELS WITH GLIOMA, AND THE USE OF MICROflUIDICS. Neuro-Oncology, 26 (Supp7). vii7-vii7. ISSN 1522-8517

Huyton, Jack, Smith, Christopher George severin ORCID: 0000-0002-6541-9035 and Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 (2024) EXPLORING LOW-DENSITY LIPOPROTEIN RECEPTOR (LDLR) FAMILY IN GLIOBLASTOMA. Neuro-Oncology, 26 (Supp7). vii7-vii7. ISSN 1522-8517

Chandler, Rebecca, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Mathews, Roshini Mariam and Stasik, Izabela ORCID: 0000-0002-7756-4731 (2024) INVESTIGATING CUDC-101 EFFECT AND MECHANISM OF ACTION AGAINST GLIOBLASTOMA IN VITRO. Neuro-Oncology, 26 (Supp7). vii16-vii16. ISSN 1522-8517

Zwain, Tamara, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Zwayen, Suha Aqeel abdulmunem, Shaw, Andrew, Burrow, Andrea Julie and Singh, Kamalinder ORCID: 0000-0001-7325-0711 (2023) Overcoming biological barriers BBB/BBTB by designing PUFA functionalised lipid-based nanocarriers for glioblastoma targeted therapy. Biomaterials Advances, 155 .

Rzepecka, Klaudia, Lawrence, Clare Louise ORCID: 0000-0003-0170-0079, Moualla, Dima, Hayes, Joseph ORCID: 0000-0002-7745-9616 and Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 (2022) Effects of Glycogen Synthase Kinase-3β (GSK3β) Inhibition in Glioblastoma Using Novel Compounds. Neuro-Oncology, 24 (Supple). iv20-iv20. ISSN 1523-5866

Lilo, Taha Luay, Medeiros-De-morais, Camilo De lelis ORCID: 0000-0003-2573-787X, Ashton, Katherine M., Davis, Charles, Dawson, Timothy P., Martin, Francis L., Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Roberts, Gareth, Ray, Arup et al (2022) Raman hyperspectral imaging coupled to three-dimensional discriminant analysis: classification of meningiomas brain tumour grades. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy . ISSN 1386-1425

Pritchard, Anna ORCID: 0000-0002-6280-7008, Fabian, Zsolt ORCID: 0000-0002-4973-9872, Lawrence, Clare Louise ORCID: 0000-0003-0170-0079, Morton, Glyn, Crean, Stjohn ORCID: 0000-0001-9336-8549 and Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 (2022) An Investigation into the Effects of Outer Membrane Vesicles and Lipopolysaccharide of Porphyromonas gingivalis on Blood-Brain Barrier Integrity, Permeability, and Disruption of Scaffolding Proteins in a Human in vitro Model. Journal of Alzheimer's Disease . pp. 1-22. ISSN 1387-2877

Kouki, Mhd Ammar, Pritchard, Anna ORCID: 0000-0002-6280-7008, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 and Crean, Stjohn ORCID: 0000-0001-9336-8549 (2021) Do Periodontal Pathogens or Associated Virulence Factors Have a Deleterious Effect on the Blood-Brain Barrier, Contributing to Alzheimer’s Disease? Journal of Alzheimer's Disease . ISSN 1387-2877

Davies, Matthew P, Benitez, Rocio, Perez, Concepcion, Jakupovic, Sven, Welsby, Philip John ORCID: 0000-0002-2110-8198, Rzepecka, Klaudia Magdalena, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Davidson, Colin ORCID: 0000-0002-8180-7943, Martinez, Ana et al (2021) Structure-Based Design of Potent Selective Nanomolar Type-II Inhibitors of Glycogen Synthase Kinase-3β. Journal of Medicinal Chemistry, 64 (3). pp. 1497-1509. ISSN 0022-2623

Zwain, Tamara, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Sabagh, Bassem, Shaw, Andrew, Burrow, Andrea Julie and Singh, Kamalinder ORCID: 0000-0001-7325-0711 (2021) Tailoring functional nanostructured lipid carriers for glioblastoma treatment with enhanced permeability through in-vitro 3D BBB/BBTB models. Materials Science and Engineering: C, 121 (111774). ISSN 0928-4931

Esposito, Carla L., Nuzzo, Silvia, Kumar, Swati A., Rienzo, Anna, Lawrence, Clare Louise ORCID: 0000-0003-0170-0079, Pallini, Roberto, Shaw, Lisa ORCID: 0000-0002-6226-6467, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Ricci-Vitiani, Lucia et al (2016) A combined microRNA-based targeted therapeutic approach to eradicate glioblastoma stem-like cells. Journal of Controlled Release, 238 . pp. 43-57. ISSN 0168-3659

Aptekar, Shraddha Ashok, Arora, Mphit, Lawrence, Clare Louise ORCID: 0000-0003-0170-0079, Lea, Robert William, Ashton, K, Dawson, Tim, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 and Shaw, Lisa ORCID: 0000-0002-6226-6467 (2015) Selective Targeting to Glioma with Nucleic Acid Aptamers. PloS one, 10 (8). e0134957. ISSN 1932-6203

Hayes, Josie, Thygesen, Helene, Tumilson, Charlotte, Droop, Alastair, Boissinot, Marjorie, Hughes, Thomas A., Westhead, David, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Shaw, Lisa ORCID: 0000-0002-6226-6467 et al (2014) Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature. Molecular Oncology, 9 (3). pp. 704-714. ISSN 1574-7891

Tumilson, Charlotte A., Lea, Robert W., Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 and Shaw, Lisa (2014) Circulating MicroRNA Biomarkers for Glioma and Predicting Response to Therapy. Molecular Neurobiology, 50 (2). pp. 545-558. ISSN 0893-7648

Lappin, Graham, Shishikura, Yoko, Jochemsen, Roeline, Weaver, Richard John, Gesson, Charlotte, Houston, J. Brian, Oosterhuis, Berend, Bjerrum, Ole J., Grynkiewicz, Grzegorz et al (2011) Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen), and phenobarbital in human volunteers. European Journal of Pharmaceutical Sciences, 43 (3). pp. 141-150. ISSN 09280987

Newman, William G, Payne, Katherine, Tricker, Karen, Roberts, Stephen A, Fargher, Emily, Pushpakom, Sudeep, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Sidgwick, Gary P, Payne, Debbie et al (2011) A pragmatic randomized controlled trial of thiopurine methyltransferase genotyping prior to azathioprine treatment: the TARGET study. Pharmacogenomics, 12 (6). pp. 815-826. ISSN 1462-2416

Brown, Hayley S., Wilby, Alison J., Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 and Houston, J. Brian (2010) Comparative Use of Isolated Hepatocytes and Hepatic Microsomes for Cytochrome P450 Inhibition Studies: Transporter-Enzyme Interplay. Drug Metabolism and Disposition, 38 (12). pp. 2139-2146. ISSN 0090-9556

Baxter, Melissa A., Rowe, Cliff, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Harrison, Sean, Hanley, Karen Piper, Park, B. Kevin, Kitteringham, Neil R., Goldring, Chris E. and Hanley, Neil A. (2010) Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening. Stem Cell Research, 5 (1). pp. 4-22. ISSN 1873-5061

Book Section

Kouki, Mhd Ammar, Pritchard, Anna Barlach, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349 and Crean, Stjohn ORCID: 0000-0001-9336-8549 (2022) Do Periodontal Pathogens or Associated Virulence Factors Have a Deleterious Effect on the Blood-Brain Barrier, Contributing to Alzheimer’s Disease? In: Advances in Alzheimer’s Disease. IOS Press, pp. 673-689.