Chetter, Ben, Kyriakis, Efthimios, Barr, Daniel, Karra, Aikaterini G., Katsidou, Elisabeth, Koulas, Symeon M., Skamnaki, Vassiliki T., Snape, Timothy James ORCID: 0000-0003-2766-4491, Psarra, Anna-Maria G. et al
(2020)
Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors.
Bioorganic Chemistry, 102
(104003).
ISSN 0045-2068
Barr, Daniel, Szennyes, Eszter, Bokor, Éva, Al-Oanzi, Ziad H., Moffatt, Colin, Kun, Sándor, Docsa, Tibor, Sipos, Ádám, Davies, Matthew et al (2019) Identification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies. ACS Chemical Biology, 14 (7). pp. 1460-1470. ISSN 1554-8929
Sherer, Christopher ORCID: 0000-0002-6422-9870, Prabhu, Saurabh, Adams, David R, Hayes, Joseph
ORCID: 0000-0002-7745-9616, Rowther, Farzana, Tolaymat, Ibrahim, Warr, Tracy and Snape, Timothy James
ORCID: 0000-0003-2766-4491
(2018)
Towards identifying potent new hits for glioblastoma.
MedChemComm, 9
(11).
pp. 1850-1861.
ISSN 2040-2503
Sherer, Christopher ORCID: 0000-0002-6422-9870, Tolaymat, Ibrahim, Rowther, Farzana, Warr, Tracy and Snape, Timothy James
ORCID: 0000-0003-2766-4491
(2017)
Preliminary SAR on indole-3-carbinol and related fragments reveals a novel anticancer lead compound against resistant glioblastoma cells.
Bioorganic & Medicinal Chemistry Letters, 27
(7).
pp. 1561-1565.
ISSN 0960-894X
Snape, Timothy James ORCID: 0000-0003-2766-4491, Dennison, Sarah Rachel
ORCID: 0000-0003-4863-9607 and Patil--sen, Yogita
ORCID: 0000-0002-4286-8874
(2016)
Functional foldamers that target bacterial membranes: the effect of charge, amphiphilicity and conformation.
Bioorganic & Medicinal Chemistry, 24
(18).
pp. 4241-4245.
ISSN 0968-0896
Harris, Frederick, Prabhu, Saurabh, Dennison, Sarah Rachel ORCID: 0000-0003-4863-9607, Snape, Timothy James
ORCID: 0000-0003-2766-4491, Lea, Robert William, Mura, Manuela and Phoenix, David Andrew
(2016)
Anionic Host Defence Peptides from the Plant Kingdom: Their Anticancer Activity and Mechanisms of Action.
Protein and Peptide Letters, 23
(8).
pp. 676-687.
ISSN 0929-8665
Fahs, Sara, Patil-Sen, Yogita ORCID: 0000-0002-4286-8874 and Snape, Timothy J.
ORCID: 0000-0003-2766-4491
(2015)
Foldamers as Anticancer Therapeutics: Targeting Protein-Protein Interactions and the Cell Membrane.
ChemBioChem, 16
(13).
pp. 1840-1853.
ISSN 14394227
Hester, Theodore James, Dennison, Sarah Rachel ORCID: 0000-0003-4863-9607, Baker, Matthew
ORCID: 0000-0003-2362-8581 and Snape, Timothy James
ORCID: 0000-0003-2766-4491
(2015)
Functionalising the azobenzene motif delivers a light-responsive membrane-interactive compound with the potential for photodynamic therapy applications.
Organic Biomolecular Chemistry, 13
(29).
pp. 8067-8070.
ISSN 1477-0520
Sherer, Chris and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2015)
Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives.
European Journal of Medicinal Chemistry, 97
.
pp. 552-560.
ISSN 02235234
Ameen, Dana and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2015)
A Baker–Venkataraman retro-Claisen cascade delivers a novel alkyl migration process for the synthesis of amides.
Tetrahedron Letters, 56
(14).
pp. 1816-1819.
ISSN 00404039
Snape, Timothy J. ORCID: 0000-0003-2766-4491 and Warr, Tracy
(2014)
Approaches Toward Improving the Prognosis of Pediatric Patients With Glioma: Pursuing Mutant Drug Targets With Emerging Small Molecules.
Seminars in Pediatric Neurology, 22
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pp. 28-34.
Prabhu, Saurabh, Dennison, Sarah Rachel ORCID: 0000-0003-4863-9607, Mura, Manuela
ORCID: 0000-0002-3913-7595, Lea, Robert William, Snape, Timothy James
ORCID: 0000-0003-2766-4491 and Harris, Frederick
(2014)
Cn-AMP2 from green coconut water is an anionic anticancer peptide.
Journal of Peptide Science, 20
(12).
pp. 909-915.
ISSN 1075-2617
Snape, Timothy James ORCID: 0000-0003-2766-4491, Fahs, Sara, Rowther, Farjana, Dennison, Sarah Rachel
ORCID: 0000-0003-4863-9607, Patil-Sen, Yogita and Warr, Tracy
(2014)
Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity.
Bioorganic & Medicinal Chemistry Letters, 24
(15).
pp. 3430-3433.
ISSN 0960-894X
Ameen, Dana and Snape, Timothy James ORCID: 0000-0003-2766-4491
(2014)
Developing the Scope of O→C Aryl Migrations: Exploring Amide Substrates as Potential Precursors for Asymmetric Reactions.
European Journal of Organic Chemistry, 2014
(9).
pp. 1925-1934.
ISSN 1434-193X
Lal, Samridhi and Snape, Timothy James ORCID: 0000-0003-2766-4491
(2014)
Aromatic amides and ureas as novel molecular probes for diagnosing disease.
Medical Hypotheses, 83
(6).
pp. 751-754.
ISSN 03069877
Snape, Timothy James ORCID: 0000-0003-2766-4491 and Ameen, Dana
(2014)
Mechanism and Application of Baker–Venkataraman O→C Acyl Migration Reactions.
Synthesis, 47
(02).
pp. 141-158.
ISSN 0039-7881
Prabhu, Saurabh, Harris, Frederick, Lea, Robert William and Snape, Timothy James ORCID: 0000-0003-2766-4491
(2014)
Small-molecule clinical trial candidates for the treatment of glioma.
Drug Discovery Today, 19
(9).
pp. 1298-1308.
ISSN 13596446
Prabhu, Saurabh, Dennison, Sarah R., Lea, Bob, Snape, Timothy J. ORCID: 0000-0003-2766-4491, Nicholl, Iain D., Radecka, Iza and Harris, Frederick
(2013)
Anionic Antimicrobial and Anticancer Peptides from Plants.
Critical Reviews in Plant Sciences, 32
(5).
pp. 303-320.
ISSN 0735-2689
Ameen, Dana and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2013)
Chiral 1,1-diaryl compounds as important pharmacophores.
MedChemComm, 4
(6).
p. 893.
ISSN 2040-2503
Prabhu, Saurabh, Akbar, Zaheer, Harris, Frederick, Karakoula, Katherine, Lea, Robert, Rowther, Farzana, Warr, Tracy and Snape, Timothy ORCID: 0000-0003-2766-4491
(2013)
Preliminary biological evaluation and mechanism of action studies of selected 2-arylindoles against glioblastoma.
Bioorganic & Medicinal Chemistry, 21
(7).
pp. 1918-1924.
ISSN 09680896
Dennison, Sarah R., Phoenix, David A. and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2013)
Synthetic oligoureas of metaphenylenediamine mimic host defence peptides in their antimicrobial behaviour.
Bioorganic & Medicinal Chemistry Letters, 23
(9).
pp. 2518-2521.
ISSN 0960894X
Lal, Samridhi and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2012)
Exploitation of a Candida antarctica lipase B-catalysed in situ carboxylic acid activation method for the synthesis of acetanilides.
Journal of Molecular Catalysis B: Enzymatic, 83
.
pp. 80-86.
ISSN 13811177
Snape, Timothy J. ORCID: 0000-0003-2766-4491, Karakoula, Katherine, Rowther, Farzana and Warr, Tracy
(2012)
Exploiting conformationally restricted N,N′-dimethyl-N,N′-diarylureas as biologically active CC double bond analogues: synthesis and biological evaluation of combretastatin A-4 analogues.
RSC Advances, 2
(19).
p. 7557.
ISSN 2046-2069
Dennison, Sarah R., Akbar, Zaheer, Phoenix, David A. and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2012)
Interactions between suitably functionalised conformationally distinct benzanilides and phospholipid monolayers.
Soft Matter, 8
(11).
p. 3258.
ISSN 1744-683X
Snape, Timothy ORCID: 0000-0003-2766-4491, March-Cortijos, Andrea and Turner, Nicholas
(2012)
Synthesis of 1,3-Disubstituted Azetidines via a Tandem Ring-Opening Ring-Closing Procedure.
Synlett, 23
(10).
pp. 1511-1515.
ISSN 0936-5214
Dennison, Sarah R., Snape, Timothy J. ORCID: 0000-0003-2766-4491 and Phoenix, David A.
(2012)
Thermodynamic interactions of a cis and trans benzanilide with Escherichia coli bacterial membranes.
European Biophysics Journal, 41
(8).
pp. 687-693.
ISSN 0175-7571
Harris, Frederick, Prabhu, Saurabh, Lea, Robert William and Snape, Timothy James ORCID: 0000-0003-2766-4491
(2011)
Characterisation of an anionic antimicrobial peptide isolated from green coconut water.
In: UK-Netherlands Joint Symposium on Antimicrobial peptides: Isolation, characterization, modification and applications, 2011, University of Durham.
Prabhu, Saurabh, Harris, Frederick, Lea, Robert William and Snape, Timothy James ORCID: 0000-0003-2766-4491
(2011)
Towards establishing the effects and mechanism of action of a series of substituted indoles in an in vitro chemosensitivity system for glioma treatment.
In: Britsh Neuro-Oncology Annual Meeting, 2011, University of Glagow.
Ellis, Andrew J, Reiss, Renate, Snape, Timothy James ORCID: 0000-0003-2766-4491 and Turner, Nicholas
(2009)
Monoamine oxidase (MAO-N) catalysed reactions: application towards the chemo-enzymatic deracemisation of the alkaloid (+)- crispine A.
In:
Practical methods for biocatalysis and biotransformations.
Wiley, London, pp. 319-322.
ISBN 0470519274
March-Cortijos, Andrea and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2009)
Towards a chemo-enzymatic method for the asymmetric synthesis of β-amino tertiary alcohols.
Organic & Biomolecular Chemistry, 7
(24).
pp. 5163-5165.
ISSN 1477-0520
March-Cortijos, Andrea and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2009)
Towards a chemo-enzymatic method for the asymmetric synthesis of β-amino tertiary alcohols.
Organic & Biomolecular Chemistry, 7
(24).
p. 5163.
ISSN 1477-0520
Deplanche, K, Snape, Timothy James ORCID: 0000-0003-2766-4491, Hazrati, S., Harrad, S. and Macaskie, L. E.
(2009)
Versatility of a new bioinorganic catalyst: Palladized cells of Desulfovibrio desulfuricans and application to dehalogenation of flame retardant materials.
Environmental Technology, 30
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p. 681.
ISSN 0959-3330
Deplanche, K., Snape, T.J. ORCID: 0000-0003-2766-4491, Hazrati, S., Harrad, S. and Macaskie, L.E.
(2009)
Versatility of a new bioinorganic catalyst: Palladized cells ofDesulfovibrio desulfuricansand application to dehalogenation of flame retardant materials.
Environmental Technology, 30
(7).
pp. 681-692.
ISSN 0959-3330
Clayden, Jonathan, Lemiègre, Loïc, Morris, Gareth A., Pickworth, Mark, Snape, Timothy J. ORCID: 0000-0003-2766-4491 and Jones, Lyn
(2008)
Helix Persistence and Breakdown in Oligoureas of Metaphenylenediamine: Apparent Diastereotopicity as a Spectroscopic Marker of Helix Length in Solution.
Journal of the American Chemical Society, 130
(45).
pp. 15193-15202.
ISSN 0002-7863
Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2008)
A truce on the Smiles rearrangement: revisiting an old reaction—the Truce–Smiles rearrangement.
Chemical Society Reviews, 37
(11).
pp. 2452-2458.
ISSN 0306-0012
Snape, Timothy ORCID: 0000-0003-2766-4491
(2008)
α-Arylation of Aryl Ketones: Expanding the Scope of the Truce-Smiles Rearrangement.
Synlett, 2008
(17).
pp. 2689-2691.
ISSN 0936-5214
Cortijos, Andrea March and Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2008)
Enzymatic desymmetrisation of (2-hydroxymethyl-oxiranyl)-methanol in organic solvents.
Tetrahedron: Asymmetry, 19
(15).
pp. 1761-1763.
ISSN 09574166
Creamer, N.J., Deplanche, K., Snape, T.J. ORCID: 0000-0003-2766-4491, Mikheenko, I.P., Yong, P., Samyahumbi, D., Wood, J., Pollmann, K., Selenska-Pobell, S. et al
(2008)
A biogenic catalyst for hydrogenation, reduction and selective dehalogenation in non-aqueous solvents.
Hydrometallurgy, 94
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pp. 138-143.
ISSN 0304386X
Betson, Mark S., Bracegirdle, Ann, Clayden, Jonathan, Helliwell, Madeleine, Lund, Andrew, Pickworth, Mark, Snape, Timothy J. ORCID: 0000-0003-2766-4491 and Worrall, Christopher P.
(2007)
Achieving conformational control over C?C, C?N and C?O bonds in biaryls, N,N?-diarylureas and diaryl ethers: advantages of a relay axis.
Chemical Communications
(7).
p. 754.
ISSN 1359-7345
Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2007)
Recent advances in the semi-pinacol rearrangement of α-hydroxy epoxides and related compounds.
Chemical Society Reviews, 36
(11).
p. 1823.
ISSN 0306-0012
Bailey, Kevin R., Ellis, Andrew J., Reiss, Renate, Snape, Timothy J. ORCID: 0000-0003-2766-4491 and Turner, Nicholas J.
(2007)
A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine A.
Chemical Communications
(35).
p. 3640.
ISSN 1359-7345
Snape, Timothy J. ORCID: 0000-0003-2766-4491
(2006)
Application of the semi-pinacol rearrangement towards the generation of alkenyl-substituted quaternary carbon centres.
Organic & Biomolecular Chemistry, 4
(22).
p. 4144.
ISSN 1477-0520
Ciucci, A., Gianferretti, P., Piva, R., Guyot, T., Snape, T. J. ORCID: 0000-0003-2766-4491, Roberts, S. M. and Santoro, M. G.
(2006)
Induction of Apoptosis in Estrogen Receptor-Negative Breast Cancer Cells by Natural and Synthetic Cyclopentenones: Role of the I B Kinase/Nuclear Factor- B Pathway.
Molecular Pharmacology, 70
(5).
pp. 1812-1821.
ISSN 0026-895X
Bickley, Jamie F, Roberts, Stanley M, Santoro, M.Gabriella and Snape, Timothy J ORCID: 0000-0003-2766-4491
(2004)
Synthesis and revision of the stereochemistry of a cyclopentenone natural product isolated from ascomycete strain A23-98.
Tetrahedron, 60
(11).
pp. 2569-2576.
ISSN 00404020
Dauvergne, Jérôme, Happe, Alan M, Jadhav, Vasudev, Justice, David, Matos, Marie-Christine, McCormack, Peter J, Pitts, Michael R, Roberts, Stanley M, Singh, Sanjay K et al (2004) Synthesis of 4-azacyclopent-2-enones and 5,5-dialkyl-4-azacyclopent-2-enones. Tetrahedron, 60 (11). pp. 2559-2567. ISSN 00404020