Rapidly mutating Y-STRs multiplex genotyping panel to investigate UAE population

Alghafri, Rashed Hamdan Nasser h-binamma, Goodwin, William H orcid iconORCID: 0000-0002-3632-3552 and Hadi, Ss orcid iconORCID: 0000-0002-2994-3083 (2013) Rapidly mutating Y-STRs multiplex genotyping panel to investigate UAE population. Forensic Science International: Genetics Supplement Series, 4 (1). e200-e201. ISSN 1875-1768

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Official URL: https://doi.org/10.1016/j.fsigss.2013.10.103


Development of a new multiplex comprising of 13 Rapidly Mutating Y STRs (RM Y-STR) is presented. The multiplex will aid investigating the human genetic structure of United Arab Emirates (UAE) populations and would also be used to investigate unresolved forensic cases in Dubai Forensic Laboratory. Thirteen markers have been included in the multiplex. A mini validation of the new multiplex has been carried out including specificity, sensitivity and mixture studies. These markers have been analysed in 600 male samples from UAE population. Allelic frequencies, haplotype diversity and discrimination capacity were determined for the 13 RM Y-STRs. Mutations pattern analysis of the RM Y-STR loci in a typical UAE family has also been carried out

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