Computational Non-Newtonian Hemodynamics of Small Vessels

Whitty, J. P. M., Wain, R. A. J., Fsadni, A., Simo, Jules orcid iconORCID: 0000-0002-1489-5920 and Francis, J. (2016) Computational Non-Newtonian Hemodynamics of Small Vessels. Journal of Bioinformatics Computational and Systems Biology, 1 (1). p. 103.

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The significance of non-Newtonian hemodynamics of small blood vessels is addressed via the description and critical discussion of cogent models within Computational Fluid Dynamics (CFD) software, in this case ANSYS-CFX. Several applicable hemodynamical shear-thinning models are presented and the relevance with respect to prediction of Shear Strain Rate (SSR) rigorously examined, in order to critically evaluate salient literature. It is found that the small vessels explored, in line with the aforementioned literature, that non-Newtionian evaluation of the fluid behavior is indeed negligible. The work presented herein is a precursor to investigation of more complex geometries and hemodynamic simulations, which are being actively researched. This is a technical note which attempts to address the significance of Newtonian/non-Newtonian flows in small blood vessels.

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