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Sonnenschein, Eva C., Stierhof, Marc, Goralczyk, Stephan, Vabre, Floriane M., Pellissier, Leonie, Hanssen, Kine Østnes, de la Cruz, Mercedes, Díaz, Caridad, de Witte, Peter et al (2017) Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040. Tetrahedron, 73 (18). pp. 2633-2637. ISSN 0040-4020
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Official URL: https://doi.org/10.1016/j.tet.2017.03.051
Abstract
A new siderophore containing a 4,5-dihydroimidazole moiety was isolated from Pseudoalteromonas piscicida S2040 together with myxochelins A and B, alteramide A and its cycloaddition product, and bromo- and dibromoalterochromides. The structure of pseudochelin A was established by spectroscopic techniques including 2D NMR and MS/MS fragmentation data. In bioassays selected fractions of the crude extract of S2040 inhibited the opportunistic pathogen Pseudomonas aeruginosa. Pseudochelin A displayed siderophore activity in the chrome azurol S assay at concentrations higher than 50 μM, and showed weak activity against the fungus Aspergillus fumigatus, but did not display antibacterial, anti-inflammatory or anticonvulsant activity.
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