New nodulopeptins from Nodularia spumigena KAC 66

Schumacher, Marc, Wilson, Neil, Tabudravu, Jioji orcid iconORCID: 0000-0002-6930-6572, Edwards, Christine, Lawton, Linda A., Motti, Cherie, Wright, Anthony D., Diederich, Marc and Jaspars, Marcel (2011) New nodulopeptins from Nodularia spumigena KAC 66. Tetrahedron, 68 (5). pp. 1622-1628. ISSN 0040-4020

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Investigation of aqueous methanol extracts of the cyanobacterium Nodularia spumigena KAC 66 led to the isolation of the nodulopeptins 899, 901 and 917. The chemical structures were determined using high-resolution NMR and MS-data. The stereochemistry of the amino-acid residues was realized by LC–MS analysis using Marfey’s reagent. The bioactivity of the novel compounds was determined.

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