A clinical case series investigating the effectiveness of an exercise intervention in chronic inflammatory demyelinating polyneuropathy (CIDP)

Janssen, Jessica orcid iconORCID: 0000-0002-5961-2736, Bunce, Megan, Nixon, John, Dunbar, Amanda Jane, Jones, Sam, Benstead, Jackie, Jeanes, Yvonne, Selfe, James and Richards, James orcid iconORCID: 0000-0002-4004-3115 (2018) A clinical case series investigating the effectiveness of an exercise intervention in chronic inflammatory demyelinating polyneuropathy (CIDP). Physiotherapy Practice and Research, 39 (1). pp. 37-44. ISSN 2213-0683

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Official URL: https://doi.org/10.3233/ppr-170100

Abstract

Background: Despite clinical intervention, people with chronic inflammatory demyelinating polyneuropathy (CIDP) experience difficulties in gait and balance on a daily basis. However, the effects on these variables of a tailored home based exercise programme for this population have not been investigated. This case series aims to investigate the effects of a home based tailored exercise programme on gait and balance in people with CIDP.
Methods: Case series of seven people with CIDP from a neurology department of a local hospital. Participants took part in a 6 week Otago exercise programme, which include walking, strengthening and balance tasks. Participants were assessed 10 times; 3 times prior, 3 times during an exercise intervention, 3 times post intervention and once at three months follow up. The outcome measures were Berg Balance scale, 10 meter walk test, fatigue severity scale and EQ-5D-5L.
Results: Participants showed an increase in walking speed and balance after the exercise intervention and most kept these improvements at 3 months follow up.
Conclusion: This study shows that exercise can be beneficial for gait and balance in people with CIDP. These findings are in line with literature from related diseases such as Guillain-Barre Syndrome. However studies with a larger sample size are needed to confirm these findings in the population.


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