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Purealidin S and Purpuramine J, Bromotyrosine Alkaloids from the Fijian Marine Sponge Druinella sp.

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Tabudravu, Jioji ORCID: 0000-0002-6930-6572 and Jaspars, Marcel (2002) Purealidin S and Purpuramine J, Bromotyrosine Alkaloids from the Fijian Marine Sponge Druinella sp. Journal of Natural Products, 65 (12). pp. 1798-1801. ISSN 0163-3864

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Official URL: https://doi.org/10.1021/np020275n

Abstract

Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.

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