Wainunuamide, a histidine-containing proline-rich cyclic heptapeptide isolated from the Fijian marine sponge Stylotella aurantium

Tabudravu, Jioji orcid iconORCID: 0000-0002-6930-6572, A. Morris, Linda, Kettenes-van den Bosch, J.Jantina and Jaspars, Marcel (2001) Wainunuamide, a histidine-containing proline-rich cyclic heptapeptide isolated from the Fijian marine sponge Stylotella aurantium. Tetrahedron Letters, 42 (52). pp. 9273-9276. ISSN 0040-4039

Full text not available from this repository.

Official URL: https://doi.org/10.1016/S0040-4039(01)01993-1

Abstract

The isolation and structure determination of an unusual cyclic heptapeptide, wainunuamide, from a Fijian marine sponge, Stylotella aurantium, is reported. The peptide contains three proline residues and a histidine residue, which is rare in cyclic peptides and has only previously been reported in a cyclic peptide isolated from the cyanobacterium Oscillatoria agardhii, suggesting a possible source of the peptide. Wainunuamide is found to have weak cytotoxic activity.
The isolation and structure determination of an unusual cyclic heptapeptide, wainunuamide, from a Fijian marine sponge, Stylotella aurantium, is reported.


Repository Staff Only: item control page