Probiotics for maintenance of remission in ulcerative colitis

Iheozor-Ejiofor, Zipporah, Kaur, Lakhbir, Gordon, Morris orcid iconORCID: 0000-0002-1216-5158, Baines, Patricia Anne, Sinopoulou, Vasiliki orcid iconORCID: 0000-0002-2831-9406 and Akobeng, Anthony K (2020) Probiotics for maintenance of remission in ulcerative colitis. Cochrane Database of Systematic Reviews .

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Ulcerative colitis is an inflammatory condition affecting the colon, with an annual incidence of approximately 10 to 20 per 100,000 people. The majority of people with ulcerative colitis can be put into remission, leaving a group who do not respond to first‐ or second‐line therapies. There is a significant proportion of people who experience adverse effects with current therapies. Consequently, new alternatives for the treatment of ulcerative colitis are constantly being sought. Probiotics are live microbial feed supplements that may beneficially affect the host by improving intestinal microbial balance, enhancing gut barrier function and improving local immune response.

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