(Mes-Acr-Me)+ClO4– Catalyzed Visible Light-Supported, One-Pot Green Synthesis of 1,8-Naphthyridine-3-Carbonitriles

Tabassum, Sumaiya, Govindaraju, Santhosh and Kendrekar, Pravin (2022) (Mes-Acr-Me)+ClO4– Catalyzed Visible Light-Supported, One-Pot Green Synthesis of 1,8-Naphthyridine-3-Carbonitriles. Topics in Catalysis . ISSN 1022-5528

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Official URL: https://doi.org/10.1007/s11244-022-01583-9


A novel, four-component one-pot green synthesis of biologically active 1,8-naphthyridines by a reaction of diverse aromatic aldehyde, malononitrile, 4-hydroxy substituted 1,6-dimethylpyridin-2(1H)-one, corresponding aniline in EtOH catalyzed by 9-Mesityl-10-methylacridinium perchlorate [(Mes-Acr-Me)+ClO4–] under visible light generated from a 24 W Blue LED wavelength 450–460 nm at 26 °C is reported. In contrast with the reported procedure, our methodology is diverse, versatile and has several favourable factors such as metal-free, excellent yields, shorter reaction durations, chromatography free and straightforward extraction process.

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