Selective Serotonin Reuptake Inhibitors for Stroke Recovery

Hua, Xing, Wu, Simiao, Legg, Lynn A., Rudberg, Ann-Sofie, Hackett, Maree orcid iconORCID: 0000-0003-1211-9087, Tilney, Russel, Lindgren, Linnea, Kutlubaev, Mansur A., Hsieh, Cheng-Fang et al (2022) Selective Serotonin Reuptake Inhibitors for Stroke Recovery. Stroke, 53 (9). e426-e428. ISSN 1524-4628

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Stroke is a major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression and other mood disorders after stroke. Small studies suggested that SSRIs might also promote motor recovery by direct effects on the brain. In this Cochrane review, we aimed to determine the effects of SSRIs in improving outcomes in people <12 months after stroke and to determine whether treatment with SSRIs is associated with adverse effects.

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