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Almeida, Osvaldo P., Hankey, Graeme J., Ford, Andrew, Etherton-Beer, Christopher, Flicker, Leon and Hackett, Maree 
ORCID: 0000-0003-1211-9087
(2022)
Wishing to die or self-harm after stroke: A planned secondary analysis of the AFFINITY Randomised Controlled Trial.
Maturitas, 166
.
pp. 86-88.
ISSN 0378-5122
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Official URL: https://doi.org/10.1016/j.maturitas.2022.08.011
Abstract
We investigated the cumulative prevalence of self-harm ideation among stroke survivors of the AFFINITY trial. We assessed these thoughts with the last item of the PHQ-9, and functional impairment with the modified Rankin Scale (mRS). Of 1221 participants (age 63.9 ± 12.3 years, 775 men), 11 reported wishing to die or self-harm at baseline. By week 52, 36 of 1159 surviving participants had reported wishing to die or self-harm. Treatment with fluoxetine for 26 weeks did not change the prevalence of these thoughts compared with placebo. Clinically significant symptoms of depression were present in 95 % of participants with recurrent self-harm thoughts.
The study was registered with the Australian and New Zealand Clinical Trials Registry, ACTRN12611000774921.
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