Improving cardiovascular health by replacing salt with low-sodium salt substitutes: a synthesis of existing evidence

Abstract

Globally, hypertension is a significant contributor to cardiovascular, renal diseases and death. Increased dietary salt intake raises the risk of hypertension, which in turn raises the risk of cardiovascular disease, stroke, and kidney disorders. A practical approach to minimising salt intake to lower blood pressure is to use low salt sodium substitutes. However, there is some evidence that salt substitutes may lead to adverse events such as hyperkalaemia, which can cause arrythmias and cardiac arrests. Existing evidence is unclear as to whom is at risk of harm from low sodium salt substitutes, and thus there is now a need for a concise synthesis of evidence to guide healthcare practitioners. The aim of this commentary is to summarise the efficiency of substituting low sodium salt substitutes with regular salt for lowering blood pressure in adult, children, and pregnant women.