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The Influence of Sidedness in Unilateral Cleft Lip and Palate on Mid Facial Growth at Five Years of Age

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Fell, Matthew, Chong, David, Parmar, Paras, Su, Ting-Li ORCID: 0000-0003-3311-4998, Enocson, Lars and Richard, Bruce (2024) The Influence of Sidedness in Unilateral Cleft Lip and Palate on Mid Facial Growth at Five Years of Age. The Cleft Palate Craniofacial Journal . ISSN 1055-6656

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Official URL: https://doi.org/10.1177/10556656241233220

Abstract

Objective
To determine whether facial growth at five years is different for children with a left versus right sided cleft lip and palate.
Design
Retrospective cohort study.
Setting
Seven UK regional cleft centres.
Patients
Patients born between 2000-2014 with a complete unilateral cleft lip and palate (UCLP).
Main Outcomes Measure
5-Year-Old's Index scores.
Results
378 children were included. 256 (68%) had a left sided UCLP and 122 (32%) had a right sided UCLP. 5-Year-Old's index scores ranged from 1 (good) to 5 (poor). There was a higher proportion of patients getting good scores (1 and 2) in left UCLP (43%) compared to right UCLP (37%) but there was weak evidence for a difference (Adjusted summary odds ratio 1.27, 95% CI 0.87 to 1.87; P = .22).
Conclusions
Whilst maxillary growth may be different for left versus right sided UCLP, definitive analysis requires older growth indices and arch forms.

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