Fertility Preservation :A Big Dilemma For Patients With Breast Cancer

Salehpour, Saghar, Saharkhiz, Nasrin, Hosseini, Sedigheh, Esmaeili, Samaneh, Hajizadeh, Nazanin, Majdi, Leila and Ziaee, Hasti (2024) Fertility Preservation :A Big Dilemma For Patients With Breast Cancer. Iranian Journal of Breast Diseases, 17 (1). ISSN 1735-9406

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Introduction : Breast cancer is one of the most common malignancies in women. Cytotoxic chemotherapy or drugs exert a negative effect on fertility potential. Techniques,such as ovarian suppression, oocyte and embryo freezing, InVitro Maturation, and ovarian tissue freezing, are necessary to preserve fertility.
Methods: To conduct this study, a query was conducted on Persian and English sources databases as Scoupus, Google Scholar, Pub Med, and Science Direct during the last 24 years using the following keywords: breast cancer, infertility, fertility preservation, oocyte freezing, and embryo freezing.
Results: Based on the result15% to 25% of patients are young premenopausal women. Chemotherapy or radiation therapy can lead to infertility or early menopause. As suggested by evidence, the success rate of embryo freezing is much higher than oocyte freezing and In Vitro Maturation. Among the fertility preservation methods, ovarian tissue freezing and 3D bioprinting are in the laboratory research stage and have received much attention. Correct counseling and providing accurate information to patients and their timely referral have have a marked impact on improving their mental and physical condition and treating their underlying disease.
Conclusion: As evidence by the result of this study, early diagnosis of breast cancer and timely referral to a fertility specialist enable , breast cancer patients to maintain their fertility and experience their biological child after aggressive cancer treatments.

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