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Towards Structurally New Cyanine Dyes – Investigating the Photophysical and Potential Antifungal Properties of Linear Substituted Heptamethine Dyes

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Okoh, Okoh Adeyi, Lawrence, Clare Louise ORCID: 0000-0003-0170-0079, Bisby, Roger, Brennan, Sarah-Louise and Smith, Robert B ORCID: 0000-0002-2829-5360 (2024) Towards Structurally New Cyanine Dyes – Investigating the Photophysical and Potential Antifungal Properties of Linear Substituted Heptamethine Dyes. Coloration Technology . ISSN 1472-3581

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Official URL: https://doi.org/10.1111/cote.12780

Abstract

The synthesis of a range of new linear substituted heptamethine dyes has been designed and described. The photophysical properties of all the dyes were investigated, with many exhibiting improved fluorescent quantum yields when compared with indocyanine green. Finally, growth inhibition studies were performed in the fission yeast Saccharomyces pombe, which suggests potential antifungals activity in the μM range.

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