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Developing an adaptive platform trial for evaluation of medical treatments for Crohn’s disease

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Noor, Nurulamin M., Radford, Shellie J., Choodari-Oskooei, Babak, Gordon, Morris ORCID: 0000-0002-1216-5158, Hart, Ailsa L., Hepburn, Trish, Juszczak, Ed, Lindsay, James O., Kennedy, Nicholas A. et al (2025) Developing an adaptive platform trial for evaluation of medical treatments for Crohn’s disease. Nature Reviews Gastroenterology & Hepatology . ISSN 1759-5045

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Official URL: https://doi.org/10.1038/s41575-025-01052-0

Abstract

There is emerging interest in adaptive platform trials for inflammatory bowel disease. In this Comment, we present the results of a workshop that was convened to consider the opportunities and challenges of developing a platform trial in Crohn’s disease.

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