Effects of Resistance Training on Sarcopenia Risk Among Healthy Older Adults: A Scoping Review of Physiological Mechanisms

Abstract

Sarcopenia, characterized by progressive loss of muscle mass and strength, significantly increases health risks in healthy older adults. Resistance training (RT) is believed to counteract sarcopenia through a variety of physiological mechanisms, many of which remain underexplored by public health and physiotherapy professionals. This scoping review aims to consolidate studies that have explored RT programs in mitigating sarcopenia among healthy older adults. A systematic search in four knowledge databases (Web of Science, Scopus, Embase, Cumulative Index for Nursing and Allied Health Sciences Complete) was conducted on 30 April 2024 to consolidate the evidence of RT programs to mitigate sarcopenia risk among healthy older adults. Two reviewers independently screened, consolidated, and synthesized the results based on the Arksey and O’Malley framework. We included 36 studies supporting the RT program for reducing sarcopenia risk among healthy older people. Current evidence, predominantly derived from studies with high selection bias and non-randomized designs, indicates that RT programs may enhance muscle strength in healthy older adults. However, their impact on muscle morphology and mobility appears less pronounced. The dosage and intensity of RT are critical factors influencing these health outcomes. To substantiate the health benefits of RT in healthy older adults and facilitate the translation of research findings into policy-level recommendations, further high-quality, randomized controlled trials are warranted.