Comparison of Clinical Outcomes of Two Hydraulic Calcium Silicate Cements for Pulpotomy in Cariously Exposed Permanent Teeth—A Systematic Review

Holme, William James, Pisani, Flavio orcid iconORCID: 0000-0001-5102-5548, Altamimi, Khaled orcid iconORCID: 0009-0003-3954-4291 and Kanagasingam, Shalini (2025) Comparison of Clinical Outcomes of Two Hydraulic Calcium Silicate Cements for Pulpotomy in Cariously Exposed Permanent Teeth—A Systematic Review. Australian Endodontic Journal . ISSN 1329-1947

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Official URL: https://doi.org/10.1111/aej.12968

Abstract

ABSTRACT

This systematic review analysed clinical studies to determine if Biodentine offers improved outcomes for pulpotomy in cariously exposed permanent teeth compared to MTA, supporting its potential recommendation. A systematic search of MEDLINE, Oral and Dental Sciences Source, and EMBASE was conducted. Inclusion and exclusion criteria identified clinical studies comparing MTA and Biodentine for pulpotomy. The outcome measured was ‘overall success,’ based on clinical and radiographic evaluations. Two independent reviewers performed data extraction and quality assessment using the Risk of Bias 2 tool. Four randomised controlled trials with 265 teeth and follow‐up up to 6 years met the inclusion criteria. One study had a high risk of bias, whereas only one study was deemed to have a low risk of bias. No statistically significant differences were found between Biodentine and MTA. Based on our findings, Biodentine is a viable alternative to MTA, showing similar outcomes. Further long‐term clinical studies are needed to determine optimal biomaterials to improve clinical outcomes.


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