Items created by Stasik, Izabela

2024

Montalbo, Kristy, Stasik, Izabela ORCID: 0000-0002-7756-4731, Bakker, Emyr ORCID: 0000-0002-0091-1029 and Smith, Christopher George severin ORCID: 0000-0002-6541-9035 (2024) EXPLORING MOLECULAR LINKS IN BRAIN TUMOUR BIOPSY TISSUES AND ALZHEIMER’S DISEASE. Neuro-Oncology, 26 (Supp7). vii17-vii17. ISSN 1522-8517

Chandler, Rebecca, Alder, Jane Elizabeth ORCID: 0000-0003-4463-0349, Mathews, Roshini Mariam and Stasik, Izabela ORCID: 0000-0002-7756-4731 (2024) INVESTIGATING CUDC-101 EFFECT AND MECHANISM OF ACTION AGAINST GLIOBLASTOMA IN VITRO. Neuro-Oncology, 26 (Supp7). vii16-vii16. ISSN 1522-8517

Schram, Niah, Hayes, Joseph ORCID: 0000-0002-7745-9616, Antia, Imeobong ORCID: 0000-0001-6620-1903 and Stasik, Izabela ORCID: 0000-0002-7756-4731 (2024) STUDIES ON GLYCOGEN PHOSPHORYLASE AS A POTENTIAL MOLECULAR TARGET IN GLIOBLASTOMA. Neuro-Oncology, 26 (Supp7). vii17-vii17. ISSN 1522-8517

Khan, Zahra Rafiqa, Welsby, Philip J., Stasik, Izabela ORCID: 0000-0002-7756-4731 and Hayes, Joseph ORCID: 0000-0002-7745-9616 (2024) Discovery of Potent Multikinase Type-II Inhibitors Targeting CDK5 in the DFG-out Inactive State with Promising Potential against Glioblastoma. Journal of Medicinal Chemistry, 67 (9). pp. 7539-7552. ISSN 0022-2623

2023

Mathomes, Rachel Thelma ORCID: 0000-0002-1079-8509, Koulas, Symeon M., Tsialtas, Ioannis, Stravodimos, George, Welsby, Philip J., Psarra, Anna-Maria G., Stasik, Izabela ORCID: 0000-0002-7756-4731, Leonidas, Demetres D. and Hayes, Joseph ORCID: 0000-0002-7745-9616 (2023) Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its’ potential against glioblastoma in cellular models. Chemico-Biological Interactions, 382 . ISSN 0009-2797

2022

Jones, Lydia, Jones, Vicky Claire ORCID: 0000-0001-8401-5223, Shaw, Lisa ORCID: 0000-0002-6226-6467, Stasik, Izabela ORCID: 0000-0002-7756-4731 and Smith, Christopher George severin ORCID: 0000-0002-6541-9035 (2022) Brain Tumour Lessons From Alzheimer’s Disease: Beta-Amyloid and SorLA Expression in Glioblastoma (Abstract only). Neuro-Oncology, 24 (4). iv14. ISSN 1522-8517

Khan, Zahra, Stasik, Izabela ORCID: 0000-0002-7756-4731 and Hayes, Joseph ORCID: 0000-0002-7745-9616 (2022) Computer-aided Design of Novel CDK5 Inhibitors; Towards New Treatments of Glioblastoma. Neuro-Oncology, 24 (Supple). iv8-iv8. ISSN 1523-5866

Montalbo, Kristy, Bakker, Emyr ORCID: 0000-0002-0091-1029, Stasik, Izabela ORCID: 0000-0002-7756-4731 and Smith, Christopher George severin ORCID: 0000-0002-6541-9035 (2022) Exploring a Link Between Alzheimer’s and Glioma by Investigating SORL1 Network. Neuro-Oncology, 24 (Supple). iv22-iv22. ISSN 1523-5866

2016

McLaughlin, K. A., Nemeth, Z., Bradley, C. A., Humphreys, L., Stasik, Izabela ORCID: 0000-0002-7756-4731, Fenning, C., Majkut, J., Higgins, C., Crawford, N. et al (2016) FLIP: A Targetable Mediator of Resistance to Radiation in Non-Small Cell Lung Cancer. Molecular Cancer Therapeutics, 15 (10). pp. 2432-2441. ISSN 1535-7163

2014

Majkut, J., Sgobba, M., Holohan, C., Crawford, N., Logan, A. E., Kerr, E., Higgins, C. A., Redmond, K. L., Riley, J. S. et al (2014) Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly. Nature Communications, 5 . p. 3350.

2013

Riley, J S, Hutchinson, R, McArt, D G, Crawford, N, Holohan, C, Paul, I, Van Schaeybroeck, S, Salto-Tellez, M, Johnston, P G et al (2013) Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer. Cell Death and Disease, 4 (12). e951.

Crawford, N, Stasik, Izabela ORCID: 0000-0002-7756-4731, Holohan, C, Majkut, J, McGrath, M, Johnston, P G, Chessari, G, Ward, G A, Waugh, D J et al (2013) SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma. Cell Death and Disease, 4 (7). e733.

2012

Paul, I, Chacko, A D, Stasik, Izabela ORCID: 0000-0002-7756-4731, Busacca, S, Crawford, N, McCoy, F, McTavish, N, Wilson, B, Barr, M et al (2012) Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer. Cell Death and Disease, 3 (12). e449.

Belkhiri, Abbes, Muret, Jane, Hasmim, Meriem, Stasik, Izabela ORCID: 0000-0002-7756-4731, Jalil, Abdelali, Mallavialle, Aude, Nanbakhsh, Arash, Lacroix, Ludovic, Billot, Katy et al (2012) Attenuation of Soft-Tissue Sarcomas Resistance to the Cytotoxic Action of TNF-α by Restoring p53 Function. PLoS ONE, 7 (6). e38808. ISSN 1932-6203

Hurwitz, Jane L., Stasik, Izabela ORCID: 0000-0002-7756-4731, Kerr, Emma M., Holohan, Caitriona, Redmond, Kelly M., McLaughlin, Kirsty M., Busacca, Sara, Barbone, Dario, Broaddus, V. Courtney et al (2012) Vorinostat/SAHA-induced apoptosis in malignant mesothelioma is FLIP/caspase 8-dependent and HR23B-independent. European Journal of Cancer, 48 (7). pp. 1096-1107. ISSN 0959-8049

Kerr, E, Holohan, C, McLaughlin, K M, Majkut, J, Dolan, S, Redmond, K, Riley, J, McLaughlin, K, Stasik, Izabela ORCID: 0000-0002-7756-4731 et al (2012) Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis. Cell Death and Differentiation, 19 (8). pp. 1317-1327. ISSN 1350-9047

2010

Massai, Yosra, Zaeem Noman, Muhammad, Derouiche, Amine, Kourda, Nadia, Akalay, Intissar, Hasmim, Meriem, Stasik, Izabela ORCID: 0000-0002-7756-4731, Ben Jilani, Sarra, Chebil, Mohamed et al (2010) Cytokeratin 18 expression pattern correlates with renal cell carcinoma progression: Relationship with Snail. International Journal of Oncology, 36 (5). pp. 1145-1154. ISSN 1019-6439

2008

Stasik, Izabela ORCID: 0000-0002-7756-4731, Rapak, Andrzej, Zioło, Ewa and Strządała, Leon (2008) The mitochondrial localization of RelB and NFATx in immature T cells. Cellular and Molecular Biology Letters, 13 (4). ISSN 1425-8153

2007

Rapak, Andrzej, Stasik, Izabela ORCID: 0000-0002-7756-4731, Ziolo, Ewa and Strzadala, Leon (2007) Apoptosis of lymphoma cells is abolished due to blockade of cytochrome c release despite Nur77 mitochondrial targeting. Apoptosis, 12 (10). pp. 1873-1878. ISSN 1360-8185

Stasik, Izabela ORCID: 0000-0002-7756-4731, Rapak, Andrzej, Kalas, Wojciech, Ziolo, Ewa and Strzadala, Leon (2007) Ionomycin-induced apoptosis of thymocytes is independent of Nur77 NBRE or NurRE binding, but is accompanied by Nur77 mitochondrial targeting. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1773 (9). pp. 1483-1490. ISSN 0167-4889

2005

Kochel, Izabela ORCID: 0000-0002-7756-4731, Rapak, Andrzej, Ziolo, Ewa and Strzadala, Leon (2005) Nur77 nuclear import and its NBRE-binding activity in thymic lymphoma cells are regulated by different mechanisms sensitive to FK506 or HA1004. Biochemical and Biophysical Research Communications, 334 (4). pp. 1102-1106. ISSN 0006-291X