Items created by Shervington, Leroy Alexander

2022

Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583 and Ingham, Oliver (2022) Investigating the Stability of Six Phenolic TMZ Ester Analogues, Incubated in the Presence of Porcine Liver Esterase and Monitored by HPLC. Molecules, 27 (9).

2020

Dores, Filipa, Kuźmińska, Magda, Soares, Cindy, Bohus, Marton, Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583, Habashy, Rober, Pereira, Beatriz, Peak, Matthew, Isreb, Abdullah ORCID: 0000-0001-9939-6161 et al (2020) Temperature and Solvent Facilitated Extrusion Based 3D Printing for Pharmaceuticals. European Journal of Pharmaceutical Sciences, 152 (105430). ISSN 0928-0987

Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583, Ingham, Oliver and Shervington, Amal A (2020) A novel series of phenolic temozolomide (TMZ) esters with 4 to 5-fold increased potency, compared to TMZ, against glioma cells irrespective of MGMT expression†. RSC Advances, 30 (10). pp. 17561-17570.

2018

Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583, Darekar, Ashish, Shaikh, Murassa, Mathews, Roshini and Shervington, Amal A (2018) Identifying Reliable Diagnostic/Predictive Biomarkers for Rheumatoid Arthritis. Biomarker Insights, 13 . pp. 1-9. ISSN 1177-2719

2015

Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583, Patil, Harshada Shashikant and Shervington, Amal A (2015) Could the Anti-Chaperone VER155008 Replace Temozolomide for Glioma Treatment. Journal of Cancer, 6 (8). pp. 786-794. ISSN 1837-9664

2014

Munje, Chinmay, Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583, Khan, Zarine Jamsher and Shervington, Amal A (2014) Could Upregulated Hsp70 Protein Compensate for the Hsp90-Silence-Induced Cell Death in Glioma Cells? International Journal of Brain Science, 2014 . ISSN 2356-6965

2013

Mehta, Adi, Shervington, Amal A, Howl, John, Jones, Sarah and Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583 (2013) Can RNAi-mediated hsp90α knockdown in combination with 17-AAG be a therapy for glioma? FEBS Open Bio, 3 . pp. 271-278. ISSN 22115463

2011

Mehta, Adi, Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583, Munje, Chinmay and Shervington, Amal A (2011) A Novel Therapeutic Strategy for the Treatment of Glioma, Combining Chemical and Molecular Targeting of Hsp90a. Cancers, 3 (4). pp. 4228-4244. ISSN 2072-6694

Thakkar, Dipti, Shervington, Leroy ORCID: 0000-0003-0663-0583 and Shervington, Amal (2011) Proteomic Studies Coupled with RNAi Methodologies can Shed Further Light on the Downstream Effects of Telomerase in Glioma. Cancer Investigation, 29 (2). pp. 113-122. ISSN 0735-7907

2010

Cruickshanks, Nichola, Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583, Patel, Rahima, Munje, Chinmay, Thakkar, Dipti and Shervington, Amal A (2010) Can hsp90α-Targeted siRNA Combined With TMZ Be a Future Therapy for Glioma? Cancer Investigation, 28 (6). pp. 608-614. ISSN 0735-7907

2009

Shervington, Leroy A ORCID: 0000-0003-0663-0583, Smith, Nigel, Norman, Emma, Ward, Timothy, Phillips, Roger and Shervington, Amal (2009) To determine the cytotoxicity of chlorambucil and one of its nitro-derivatives, conjugated to prasterone and pregnenolone, towards eight human cancer cell-lines. European Journal of Medicinal Chemistry, 44 (7). pp. 2944-2951. ISSN 02235234

2008

Patel, Rahima, Shervington, Leroy ORCID: 0000-0003-0663-0583, Lea, Robert and Shervington, Amal (2008) Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma. Brain Research, 1188 (-). pp. 173-181. ISSN 00068993

Shervington, Amal A, Cruickshanks, Nichola, Lea, Robert William, Roberts, Gareth, Dawson, Tim and Shervington, Leroy Alexander ORCID: 0000-0003-0663-0583 (2008) Can The Lack of HSP90α Protein in Brain Normal Tissue and Cell Lines, Rationalise it as a Possible Therapeutic Target for Gliomas? Cancer Investigation, 26 (9). pp. 900-904. ISSN 0735-7907